Endocrine Abstracts

Basal insulin secretion is essential for the maintenance of fasting glucose levels, especially through inhibition of excessive hepatic glucose output. Insulin glargine U300 is a novel long acting basal insulin formulation that provides more stable effect than glargine U100. Because of the pharmacokinetic properties of glargine U300, the expected plasma insulin concentration is not achieved during the first 4 days of treatment. We report a case of diabetic ketoacidosis in the f...

Background: CHARGE Syndrome is a rare inherited congenital disorder [1]. The name reflects the initials of the clinical findings (Coloboma, Heart disease, Atresia of the choanae, Retarded growth and mental development, Genital anomalies, Ear malformations, and hearing loss). The disease has four major findings expressed as 4C; ocular coloboma, choanal atresia, cranial nerve abnormalities, and characteristic ear anomalies [2]. Objective: Here, a case of C...

Aim: The aim of the present study was to compare version 7 of ATA risk calculating tool, developed for the staging of well differentiated thyroid cancers,and is used commonly in the clinical practice with its version 8 developed in 2018 with respect to clinical staging.Material and method: 295 patients followed with the diagnosis of well differentiated thyroid cancer were included in the present study. According to pathology reports and clinical data, th...

Introduction: Primary hyperparathyroidism (PHPT) is a disease that is characterized by elevated calcium and parathyroid hormone levels. The most common cause of PHPT is the paratiroid adenoma and the first line treatment option is surgical removal of the adenoma. Rarely, the haemorrhage in the lesion may cause the spontaneous remission of the disease.Case report: A 54-year-old woman patient with fatigue was referred to our department due to calcium level...

Introduction: Struma ovarii is an uncommon ovarian neoplasm that more than half of itself is made up of thyroid tissue. In clinical trials about the disease, malign transformation has been detected at the rate of 0.5–5%. Because of the disease’s rareness, there is no absolute agreement about diagnosis and treatment of the disease.Case report: A 33-year-old woman admitted to gynecology department with abdominal pain. Her pelvic MR revealed 147&#...

Vitamin D role is not only associated with mineral metabolism and bone health but also in globally important diseases such as obesity and metabolic syndrome. The aims of this study were to investigate: i) 25(OH) vitamin D levels in obese patients with and without metabolic syndrome and compare these with levels in healthy subjects, ii) the relationship between serum 25(OH) vitamin D levels and metabolic syndrome components such as body mass index, waist circumference, blood pr...

Kidney transplant patients are prone to metabolic bone diseases. In this descriptive clinical study we aimed to evaluate the incidence of osteopenia osteoporosis, vertebral fractures in our group of renal transplant patients.Methods: Eighty seven patients (25 males and 62 females) aged from 20 to 67 years, who had undergone kidney transplantation 1 to 20 yrs. previously included in the study. Bone mineral densitometry was performed using dual-energy X-ra...

Silent thyroiditis is characterized by the destructive thyroid inflammation and is considered to be a chronic autoimmune thyroid disease, although the etiology could not have been fully explained. On the other hand, Graves’ disease is autoimmune phenomena as well as silent thyroiditis and silent thyroiditis has been classified as part of the spectrum of Graves’ disease. Although, the thyroid stimulating antibody (TSAb) are found positive in most of Graves’ disea...

Aims: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) increase the risk for diabetic ketoacidosis, particularly in patients with type 1 diabetes (T1DM). We aimed to determine whether SGLT2i use increase the risk of euglycemic diabetic ketoacidosis (euDKA) and to indicate its demographic, clinical features.Methods: We performed a retrospective cohort study of 51 patients over 18 years-old admitted to emergency unit at a tertiary care hospital from 2018...

Introduction: The etiology of gender dysphoria is still unclear. Although prior studies have shown trans men have higher androgen levels than cisgender women, they all concluded unselected populations. Our purpose to perform this study is to evaluate transmen’s hormone profile and metabolic status to compare cisgender women in a more selected population. This is the first case-controlled study to compare anthropometric, metabolic, and endocrinological parameters of drug-n...